Joan Rivers has died at age 81.
The comedian was rushed to the hospital last week after a complication with a procedure on her vocal cords.
Rivers' daughter, Melissa, released this statement:
It is with great sadness that I announce the death of my mother, Joan Rivers. She passed peacefully at 1:17 pm surrounded by family and close friends. My son and I would like to thank the doctors, nurses, and staff of Mount Sinai Hospital for the amazing care they provided for my mother.
Cooper and I have found ourselves humbled by the outpouring of love, support, and prayers we have received from around the world. They have been heard and appreciated.
My mother's greatest joy in life was to make people laugh. Although that is difficult to do right now, I know her final wish would be that we return to laughing soon.
E! reported that the "Fashion Police" host was undergoing a minor endoscopic procedure when she was transported to Mount Sinai Hospital in critical condition after going into cardiac arrest on Aug. 28.
Rivers remained at Mount Sinai where the New York Daily News reported she was on life support and later placed into a medically induced coma. Melissa Rivers previously released a statement to E! News saying her condition remained serious.
Wednesday, Rivers was moved out of intensive care and into a private room, according to a Facebook post from Melissa. NY Daily News reports Melissa made the decision to take her mother off life support.
E! and NBC Universal released the following statement:
"E! and NBCUniversal send our deepest condolences to Melissa, Cooper and her entire extended family on this incredibly sad day. For decades Joan has made people laugh, shattered glass ceilings and revolutionized comedy. She was unapologetic and fiercely dedicated to entertaining all of us and has left an indelible mark on the people that worked with her and on her legions of fans. She’s been a much beloved member of the E! family for over 20 years and the world is less funny without her in it. Today our hearts are heavy knowing Joan will not be bounding through the doors."
Rivers got her start in the '60s appearing in comedy clubs in New York City. From there, she appeared on "Candid Camera" along with "The Tonight Show" with Johnny Carson.
During this time, she was also part of the comedy trio "Jim, Jake, and Joan." The three of them were featured in the 1965 film, "Once Upon A Coffee Shop."
In the '80s, she became a regular guest host on "The Tonight Show." According to Rivers, it was Carson who told her she was "going to be a star."
She later went on to host her own brief late-night show for emerging network Fox in October 1986 that was cancelled after only a year.
In turn, Rivers started her own syndicated talk show that ran for five years and won her a Daytime Emmy for Outstanding Talk Show Host. 
Her career took a different turn in the mid-'90s when she started working for E! where she honestly and unabashedly critiqued celebrities’ looks as host of "Live from the Red Carpet" for nearly a decade.
Until her death, Rivers hosted E!’s “Fashion Police” and starred on reality series “Joan and Melissa” with her daughter.
Throughout her life, Rivers wrote more than 10 best-selling books, including '86's "Enter Talking." Her 1984 comedy album "What Becomes a Semi-Legend Most?" received a Grammy nod.
E! News Correspondent Ken Baker shared the following image of the comedian on Twitter:
SEE ALSO: An Amazing Scene From 'Louie' In Which Joan Rivers Explains Why She's A Comedian
AND: Hollywood Reacts To The Death Of Joan Rivers
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